Intraperitoneal administration of human amyloid spleen homogenate together with casein caused amyloidosis in recipient C3H mice within 5 days. The results suggest the existence of a factor accelerating induction of amyloidosis that is active across histocompatibility barriers and provide a simpler model without immunosuppressive agents for further investigations of this transfer factor.
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Shirahama et al. (1969) studied this question.
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