Why the study?
Does increasing off-time of vagal nerve stimulation improve VNS-induced sleep-disordered breathing?
Does increasing off-time of vagal nerve stimulation improve VNS-induced sleep-disordered breathing?
Increasing the off-time of vagal nerve stimulation may be an effective strategy to resolve VNS-induced sleep-disordered breathing and oxygen desaturations.
Vagal nerve stimulation (VNS) has been reported to adversely impact breathing in sleep. While continuous positive airway pressure is often employed to treat these patients, little data exist on the effects of adjusting various settings on VNS-induced sleep-disordered breathing. We describe a patient in whom increasing off-time caused resolution of VNS-induced arterial oxygen desaturations in sleep, which we believe is a novel observation.
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Bhat et al. (2012) studied this question.
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