Erosive changes of the sternal ends of the clavicles have been observed in patients with primary or secondary hyperparathyroidism. These changes may or may not be associated with erosions of the acromial ends. Careful scrutiny of the sternoclavicular areas on regular frontal chest films will usually disclose these changes, and their detection may allow a radiographic diagnosis of hyperparathyroidism from an otherwise negative chest study. Advanced rheumatoid arthritis can also produce similar erosive changes.
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Teplick et al. (1974) studied this question.