The Physiological Chemistry and Biological Activity of Nitroxyl (HNO):  The Neglected, Misunderstood, and Enigmatic Nitrogen Oxide

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTThe Physiological Chemistry and Biological Activity of Nitroxyl (HNO): The Neglected, Misunderstood, and Enigmatic Nitrogen OxideJon M. Fukuto, Michael D. Bartberger, Andrew S. Dutton, Nazareno Paolocci, David A. Wink, and K. N. HoukView Author Information Interdepartmental Program in Molecular Toxicology, UCLA School of Public Health, Los Angeles, California 90095-1772, Department of Pharmacology, UCLA School of Medicine, Center for the Health Sciences, Los Angeles, California 90095-1735, Department of Molecular Structure and Design, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, Division of Cardiology, Departments of Medicine and Biomedical Engineering, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, and Radiation Biology Branch, National Cancer Institute, Bethesda, Maryland 20892 Cite this: Chem. Res. Toxicol. 2005, 18, 5, 790–801Publication Date (Web):April 2, 2005Publication History Received16 November 2004Published online2 April 2005Published inissue 1 May 2005https://pubs.acs.org/doi/10.1021/tx0496800https://doi.org/10.1021/tx0496800review-articleACS PublicationsCopyright © 2005 American Chemical SocietyRequest reuse permissionsArticle Views1353Altmetric-Citations156LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Nitrogen,Peptides and proteins,Redox reactions,Salts,Thiols Get e-Alerts