Effect ofLactobacillus rhamnosusHN001 andBifidobacterium longumBB536 on the healthy gut microbiota composition at phyla and species level: A preliminary study

AIM: BB536 to colonize the intestinal environment of healthy subjects and modify the gut microbiota composition. METHODS: BB536 to colonize human gut microbiota was assessed by means of quantitative real-time PCR, while changes in gut microbiota composition were detected by using Ion Torrent Personal Genome Machine. RESULTS: was increased if compared to samples collected at the beginning of the experimental time course. CONCLUSION: HN001 showed the ability to modulate the gut microbiota composition, leading to a significant reduction of potentially harmful bacteria and an increase of beneficial ones. Further studies are needed to better understand the specific mechanisms involved in gut microbiota modulation.