Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
November 24, 2009Journal of Biological ChemistryOpen Access

Hsp70 and CHIP Selectively Mediate Ubiquitination and Degradation of Hypoxia-inducible Factor (HIF)-1α but Not HIF-2α

View Full Paper
Ask AI
Bookmark
Share

Authors

WLWeibo LuoSouthwestern Medical CenterJZJun ZhongGuangzhou University of Chinese MedicineRCRyan ChangJohns Hopkins University

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Luo et al. (2009) studied this question.

synapsesocial.com/papers/6a73bf4d0e7fa2a8810dd0f7https://doi.org/10.1074/jbc.m109.068577
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1p24A, a Type I Transmembrane Protein, Controls ARF1-dependent Resensitization of Protease-activated Receptor-2 by Influence on Receptor Trafficking2007 · 65 citations
  2. 2Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.1995 · 6,285 citations
  3. 3PHDs overactivation during chronic hypoxia “desensitizes” HIFα and protects cells from necrosis2008 · 262 citations
  4. 4Hypoxia Up-regulates Prolyl Hydroxylase Activity2003 · 288 citations
  5. 5An essential role for p300/CBP in the cellular response to hypoxia1996 · 805 citations