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The behavior of aqueous solutions of poly [N‐(2‐hydroxypropyl) methacrylamide], poly(N‐ethyl methacrylamide), poly(N‐ethyl acrylamide), and poly‐(triethyleneglycol monomethacrylate) was investigated and characterized in tests required for synthetic infusion solutions. The above solutions were characterized from the viewpoint of toxicity, pyrogenic properties, antigenic properties, effect on the determination of the blood groups, and effects on hemocoagulation. The elimination from blood circulation was studied on several fractions of the 14 C‐labelled poly[N‐(2‐hydroxypropyl) methacrylamide] having different molecular weights. It was found that in all tests the properties of the polymers investigated do not depart from the expected behavior.
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Kopec̆ek et al. (1973) studied this question.
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