Key result
HPLC-MS/MS detects six anticoagulant rodenticides in whole blood down to ~10 ng/mL.
Answers are grounded in this paper and cite their sources.
This paper presents a fully validated method for the qualitative identification of bromadiolone, brodifacoum, coumachlor, coumatetralyl, difenacoum and warfarin in whole blood specimens. Samples are protein precipitated with acetonitrile, processed via solid-phase extraction and analyzed by high-performance liquid chromatography with high resolution tandem mass spectrometric detection. Limits of detection were 10 ng/mL or better for all analytes.
No takes yet. Share an insight, caveat, or question.
Schaff et al. (2013) studied Anticoagulant rodenticide exposure. HPLC-HR-MS-MS analytical method was evaluated on Limit of detection for six anticoagulant rodenticides in whole blood. High-performance liquid chromatography with high-resolution tandem mass spectrometry identified six anticoagulant rodenticides in whole blood with limits of detection of 10 ng/mL or better.
Synapse has enriched 5 related papers. Consider them for comparative context: