Arterial embolism is a notable complication in patients with thyrotoxicosis and atrial fibrillation, highlighting the potential need for prophylactic anticoagulation.
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Embolism complicates thyrotoxic AF; supports anticoagulation consideration but leaves open need for randomized confirmation.
In 262 patients with thyrotoxicosis and atrial fibrillation there were 26 episodes of arterial embolism (17 cerebral and nine elsewhere) in 21 patients. Twelve incidents occurred with active thyrotoxicosis, three on reversion to sinus rhythm, and 11 after the patients were euthyroid. This important complication is more common than is realised, and most patients should be put on prophylactic anticoagulants when first seen with atrial fibrillation.
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Staffurth et al. (1977) studied this question.
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