High-Frequency Oscillatory Ventilation to Prevent Bronchopulmonary Dysplasia — Are We There Yet?

Bronchopulmonary dysplasia, also known as chronic lung disease of infancy, is an important cause of illness in preterm infants. This condition, usually defined by the need for supplemental oxygen at 36 weeks of postmenstrual age, affects nearly one third of surviving infants with extremely low birth weight (less than 1000 g) but occurs infrequently in infants with a birth weight of more than 1250 g or a gestational age of more than 30 weeks.1 Affected infants are more likely to have respiratory disorders in later infancy (including reactive airway disease and infection), to be hospitalized in the first one to . . .