Why the study?
Does a prolonged QT interval predict malignant ventricular arrhythmias in patients with acute myocardial infarction?
Does a prolonged QT interval predict malignant ventricular arrhythmias in patients with acute myocardial infarction?
Prolonged QT intervals may be valuable in predicting malignant ventricular arrhythmias in patients with acute myocardial infarction.
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May support QTc monitoring for arrhythmia risk stratification in acute MI; hypothesis-generating and requires prospective validation.
Out of a total of 947 patients admitted to the CCU at Serafimerlasarettet during 2 years, all those with AMI and vintricular fibrillation (VF) or ventricular tachycardia (VT) during the CCU stay were selected. The QT interval could be measured in 15 patients with VF and 12 with VT before the event. The QT interval was also measured in two control groups; one consisted of 27 consecutively admitted patients with AMI without ventricular arrhythmias (VA), the other of 27 non-AMI patients treated in the CCU. Most patients in the group with VA showed pathologically prolonged QT intervals and there were statistically significant differences between this group and the control groups regarding corrected mean QT intervals. If these findings are confirmed, QT measurements might be of value in the prediction of malignant VA in AMI.
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Ahnve et al. (1978) studied this question.
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