Mineral coatings are presented as a temporally controllable protein release system on a common orthopedic device material, β-tricalcium phosphate (β-TCP). Proteins are bound to coatings via electrostatic interactions and release of one or more proteins is temporally controlled in a predictable manner by modulating the physicochemical properties of mineral coatings, including morphology and dissolution rate.
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Lee et al. (2011) studied this question.
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