Interhaplotypic distance within the Monkeypox virus group and the phylogenetic relationship with the orthopoxvirus genus

In this work are used 59 haplotypes of the gene of interferon-alpha-beta receptor of Monkeypox virus, Buffalopox virus, Camelpox virus, Cowpox virus, Ectromelia virus, Rabbitpox virus, Vaccinia virus and Variola virus, recuperated the GenBank.All sequences were publicly available on the National Biotechnology Information Center (NCBI) platform.The results indicate that the methods of genetic attribution and maximum likelihood presented responses that had not been observed with the use of other methodologies.These results suggest that evolutionary actors such as the retention of ancestral polymorphism, are the responsible by the diversity among the groups studied.The Buffalopox, Ectromelia and Rabbitpox groups did not present significant structuring level and the Cowpox group presented the highest degree of haplotypic diversity.The Monkeypox group presented a poorly polymorphic pattern that, by not increasing the genetic variability of the group, also does not contribute to large variations in its protein products. .