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September 1, 1996The Journal of Clinical Endocrinology & MetabolismOpen Access

Human pancreatic islet beta-cell destruction by cytokines involves oxygen free radicals and aldehyde production.

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Authors

ARAlexander RabinovitchKelowna General HospitalWSWilma L. Suarez‐PinzonUniversity of MinnesotaKSK StrynadkaUniversity of Alberta

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Cite This Study

Rabinovitch et al. (1996) studied this question.

synapsesocial.com/papers/6a74128746f5fb0dd7eafeeehttps://doi.org/10.1210/jcem.81.9.8784069
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Destruction of Rat Islet Cell Monolayers by Cytokines: Synergistic Interactions of Interferon-γ, Tumor Necrosis Factor, Lymphotoxin, and Interleukin 11988 · 290 citations
  2. 2Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity.1987 · 303 citations
  3. 3Cytotoxic Effects of Cytokines on Human Pancreatic Islet Cells in Monolayer Culture*1990 · 169 citations
  4. 4Liposomal Delivery of Purified Heat Shock Protein hsp70 Into Rat Pancreatic Islets as Protection Against Interleukin 1β–Induced Impaired β-Cell Function1991 · 84 citations
  5. 5CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse1981 · 517 citations