Smoking and the gastrointestinal tract 'Tobacco, divine, rare, super-excellent tobacco, which goes far beyond all their panaceas, potable gold, and philosopher's stones, a sovereign remedy to all diseases. But, as it is commonly abused by most men, which take it as tinkers do ale, 'tis a plague, a mischief, a violent purger ofgoods, lands, health, hellish, devilish, and damned tobacco, the ruin and overthrow of bodv and soul.' (Anatomy of Melancholy, Robert Burton.)
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John Bennett (1972) studied this question.
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