A Review on Futuristic Scope of Agents Related to Amphibian’s Skin and Plants-based Sources in Type 2 Antidiabetic Therapies

At present, evidence suggest both amphibians' skin/plant-based treatments could be adopted as future frontline approaches to diabetes therapy. Research shows that peptides from variety of frog skin sources hold immense potential to be developed into anti diabetic agents. Host defense peptides and their derived analogues from amphibian sources like Esculentin-2Cha, Moreover, they have also been witnessed to cause significant reduction to pancreatic insulin, plasma glucagon concentrations and total body fat and plasma triglyceride levels.