MIRUMIR: an online tool to test microRNAs as biomarkers to predict survival in cancer using multiple clinical data sets

Although multiple clinical studies have correlated microRNA (miR) expression profiles with clinical outcome in cancer patients, 1 most data sets in the public domain have a complex interface, which is difficult to use by a non-specialist public and requires advanced informatics and statistical skills. Here, we present MIRUMIR, a tool which performs survival analyses and draws Kaplan–Meier (KM) plots for submitted ‘microRNA’ across several available data sets, which cover more than 800 patients. A robust statistical procedure is implemented to account for multiple testing. MIRUMIR is incorporated into BioProfiling.de, analytical portal for high-throughput cell biology, 2 and is freely available at http://www.bioprofiling.de/MIRUMIR .