Escherichia coli serogroup 0111 was isolated in 1952 as the predominant coliform organism from 5 fecal specimens obtained from 7 infants who were suffering from epidemic diarrhea of the newborn infant during two serious hospital outbreaks of this disease in 1947. The specimens had been preserved at a temperature of -40° to -70° C. for five years. The association of certain serogroups of E. coli and epidemic diarrhea of the newborn infant is discussed.
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Neter et al. (1953) studied this question.