Key result
Administration of a 12 mg adenosine bolus during a provocative test for suspected Wolff-Parkinson-White syndrome induced a self-limited 45-second episode of atrial fibrillation.
Case Report (n=1)
No
Adenosine administration during provocative testing for WPW syndrome can induce transient atrial fibrillation even in pediatric patients with otherwise normal conduction.
Warrants monitoring during adenosine WPW provocation; this Level 5 case leaves open generalizability and safety quantification.
Adenosine by rapid intravenous bolus is frequently utilized in clinical practice as both a pharmacologic treatment for supraventricular (reentrant) tachycardia and in provocative testing for the diagnosis of Wolff-Parkinson-White (WPW) syndrome. This is a case report of an otherwise healthy adolescent female who received adenosine during a provocative test for WPW syndrome. Immediately after receiving adenosine, the patient had a self-limited episode of atrial fibrillation. When administering adenosine, teams should be aware of the potential adverse effects and be prepared to treat appropriately.
No takes yet. Share an insight, caveat, or question.
Robinson et al. (2017) conducted a case report in Suspected Wolff-Parkinson-White (WPW) syndrome (n=1). Adenosine was evaluated on Induction of atrial fibrillation. Administration of a 12 mg adenosine bolus during a provocative test for suspected Wolff-Parkinson-White syndrome induced a self-limited 45-second episode of atrial fibrillation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: