Asymmetric alkylation of 2,3-alkadienyl phosphates with soft carbon nucleophiles proceeds efficiently in the presence of palladium complex catalyst bearing MeOBIPHEP or BINAP ligand to give optically active functionalized allenes up to 90% ee.
No takes yet. Share an insight, caveat, or question.
Imada et al. (2002) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: