Why the study?
Does Fredrickson-Levy-Lees (FLL) dyslipoproteinemia classification predict incident CAD in a general population cohort?
Does Fredrickson-Levy-Lees (FLL) dyslipoproteinemia classification predict incident CAD in a general population cohort?
The classical Fredrickson-Levy-Lees dyslipoproteinemia classifications, particularly type IIb, are strongly associated with incident CAD and have distinct genetic architectures.
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Type IIb pattern marks highest CAD risk in cohorts; supports FLL phenotyping for stratification but leaves open prospective validation.
Tripathi et al. (1971) studied this question.
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