Key result
The functional technique for determining neo-chord length using hydraulic tests with a sliding knot achieved satisfactory immediate hemodynamic results in 97% of patients with degenerative mitral regurgitation.
Why the study?
Does a functional hydraulic technique for determining neo-chord length provide effective and safe correction of degenerative mitral regurgitation in patients undergoing mitral valve repair?
Observational (n=34)
No
Does a functional hydraulic technique for determining neo-chord length provide effective and safe correction of degenerative mitral regurgitation in patients undergoing mitral valve repair?
A functional hydraulic technique for determining neo-chord length during mitral valve repair is safe and provides satisfactory long-term valve competence.
Supports feasibility of hydraulic neo-chord sizing in degenerative MR repair; hypothesis-generating pending randomized durability data.
Aim. To evaluate to effectiveness and safety of the functional technique of measuring the length neo-chords during reconstructive operations on the mitral valve for degenerative mitral regurgitation. Methods. The study included 34 patients, in whom the method of chord prosthesis with polytetrafluoroethylene sutures was used for correction of the anterior and/or posterior mitral valve leaflet prolapse. In order to determine the length of the chords a technique of functional hydraulic tests with a sliding suture knot was used by pressure infusion of a cold isotonic sodium chloride solution into the left ventricle until optimal geometry and competence of the valve leaflets was achieved. Results. No perioperative deaths were registered. The average postoperative length of hospital stay was 10±3.1 days. In 97% of the cases this technique made it possible to obtain immediate satisfactory hemodynamic results of the reconstruction. In long-term follow-up (13 months) 1 (3%) patient was re-operated for severe mitral regurgitation that was associated with the detachment of a native anterior leaflet chord, which was discovered during the operation. The two neo-chords epithelialized, became macroscopically indistinguishable from the native chords, and could be identified by the knots on the atrial side of the leaflet, their integrity was not compromised. In all other cases long-term follow-up after the operation showed a satisfactory hemodynamic functionality of the mitral valve. 76% of the operated patients had postoperative echocardiographic examination performed in our center. In 42% of patients there was no insufficiency, 44% of the patients had 1st degree regurgitation, in 14% of patients the regurgitation was classified as 1-2 degree with no signs of left atrium volume overload, left ventricular dysfunction or symptoms of heart failure. Conclusion. The functional technique for determining the length of neo-chords is an effective and safe method that makes it possible to successfully perform reconstructive operations for degenerative mitral regurgitation.
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Mukharyamov et al. (2012) conducted an observational in Degenerative mitral regurgitation (n=34). Functional technique for neo-chords' length determination (hydraulic tests with sliding suture knot) was evaluated on Immediate satisfactory hemodynamic results. The functional technique for determining neo-chord length using hydraulic tests with a sliding knot achieved satisfactory immediate hemodynamic results in 97% of patients with degenerative mitral regurgitation.
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