Answers are grounded in this paper and cite their sources.
The activities of carbapenems against Pseudomonas aeruginosa decreased in the presence of siliconized latex urinary catheters (SLUCs). This effect was associated with the loss of OprD. The zinc that eluted from SLUCs is responsible for this phenomenon. We have found that zinc exerts a negative effect on the expression of OprD, the porin responsible for carbapenem entry into P. aeruginosa.
No takes yet. Share an insight, caveat, or question.
Conejo et al. (2003) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: