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July 1, 1959Circulation ResearchOpen Access

Estimation of Cardiac Output from Precordial Dilution Curves in Patients with Cardiopulmonary Disease

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Why the study?

Does the precordial dilution method provide comparable precision to direct arterial dilution and Fick determinations for estimating cardiac output in patients with cardiopulmonary disease?

Population

29 patients with cardiopulmonary disease

Comparison

Precordial dilution curves for measuring flow… vs Simultaneous direct arterial dilution curves and…

Design

Cross-sectional

Authors

BSBernard F. SchreinerDartmouth CollegeFLFrank W. LovejoyStrong Memorial HospitalPYPaul N. YuFudan University

Discussion

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Implication

Precordial dilution may offer comparable precision for cardiac output estimation; leaves open prospective validation before clinical adoption.

Key Points

  • To assess the precision and reproducibility of precordial dilution curves for measuring cardiac output in comparison with standard direct arterial dilution and Fick methods.
  • Evaluated 29 patients with cardiopulmonary disease (N=29).
  • Compared blood flow rates measured via precordial dilution curves against simultaneous direct arterial dilution curves and nearly simultaneous Fick determinations.
  • Assessed the reproducibility of successive precordial flow rate determinations.
  • Measurements of flow rate obtained from precordial dilution curves showed no detectable difference in precision relative to direct arterial dilution or Fick determinations.
  • Successive precordial flow rate measurements demonstrated adequate reproducibility across repeated determinations.

Structured PICO

Does the precordial dilution method provide comparable precision to direct arterial dilution and Fick determinations for estimating cardiac output in patients with cardiopulmonary disease?

P
Population
29 patients with cardiopulmonary disease
I
Intervention
Precordial dilution curves for measuring flow rates (cardiac output)
C
Comparator
Simultaneous direct arterial dilution curves and nearly simultaneous Fick determinations
O
Outcome
Precision of flow rate measurementssurrogate

The precordial dilution method is a reproducible and comparably precise alternative to more laborious methods for estimating cardiac output.

Cite This Study

Schreiner et al. (1959) studied this question.

synapsesocial.com/papers/6a74cb88e2936089dd032cafhttps://doi.org/10.1161/01.res.7.4.595
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