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Four patients in whom visible excretion of opaque medium by the kidneys after Gasgrografin has been given by mouth are described. This was wrongly interpreted as indicating perforation of the bowel. In one case there was ulceration of the colon, but in three there was no evidence of breach of the mucosa. The unreliability of this sign as indicating perforation of the bowel is discussed.
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Douglas et al. (1968) studied this question.
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