Answers are grounded in this paper and cite their sources.
SummaryThe 30-day survival of mice exposed to a lethal dose (798 r) of x-rays was a function of the number of isologous bone-marrow cells injected. From this calibration curve it was possible to determine the surviving fraction in a suspension of marrow cells irradiated in vitro. The in vitro radiation-response of such suspensions could be represented by a typical exponential survival curve the linear part of which indicated a D37 of 84 r and an extra-polation number of 2·5.Cysteine, S,2-aminoethylisothiuronium chloride, and anoxia protected marrow cells irradiated in vitro and gave dose reduction factors ranging from 1·7–2·1. Noradrenaline did not protect the cells.
No takes yet. Share an insight, caveat, or question.
Smith et al. (1962) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: