In a Turkish cohort, patients with infective endocarditis were notably younger with a high prevalence of underlying rheumatic valvular disease compared to Western series, and the presence of echocardiographic vegetations was associated with worse clinical outcomes.
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May flag higher-risk infective endocarditis for closer monitoring; leaves open whether vegetation detection should guide therapy.
This study consists of a retrospective evaluation of microbiologic, echocardiographic, and clinical characteristics of patients with infective endocarditis seen at Türkiye Yüksek Ihtisas and SSK Ihtisas Hospitals during the previous 5 years to provide a basis for comparison with other series. The study was performed retrospectively. The mean age of the patient population, which consisted of 74 cases, was considerably low (24.6+/-12.3 yr). The majority of the patients were male (male/female = 1.96). Rheumatic valvular disease was the underlying cardiac pathosis in 66% of the cases. Congestive heart failure, embolic episodes, and mortality were more frequent among those with echocardiographically demonstrable cardiac vegetations. The microbiologic profile was considerably different from that of other series. In addition, this population showed a higher rate of congestive heart failure compared to other series. The patients with infective endocarditis in this series in the previous 5 years were found to be different from series reported from western countries.
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Heper et al. (2002) studied this question.
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