Effect of Interferon Gamma on Expression of Hla‐class Ii Molecules on Blood‐derived Dendritic Cells

T4 cells recognize antigen together with HLA class II molecules in the membrane of antigen-presenting cells (APC). The magnitude of the induced T cell response is in part dependent upon the quantitative expression of HLA-class II molecules in the cell membrane of the APC. We report here that recombinant interferon gamma (IFN-gamma) may enhance the expression of HLA class II molecules on the surface membrane of blood-derived dendritic cells by 30-90%.