Key result
Short-term exercise significantly increased absolute temperature rebound compared to rest (0.53 vs 0.04°C, P=0.04), but this dynamic response was blunted in patients with cardiac risk factors.
Why the study?
Does short-term exercise alter the reactive hyperemic response measured by digital thermal monitoring in patients scheduled for noncardiac surgery?
Observational (n=30)
Does short-term exercise alter the reactive hyperemic response measured by digital thermal monitoring in patients scheduled for noncardiac surgery?
Absolute Event Rate: 0.53% vs 0.04%
p-value: p=0.04
Short-term exercise increases the reactive hyperemic response to ischemia, but this dynamic response is blunted in patients with cardiac risk factors, suggesting potential utility for preoperative risk assessment.
Supports further study of exercise-augmented digital thermal monitoring for preoperative risk assessment; does not yet justify routine clinical use.
BACKGROUND: Perioperative vascular function has been widely studied using noninvasive techniques that measure reactive hyperemia as a surrogate marker of vascular function. However, studies are limited to a static setting with patients tested at rest. We hypothesized that exercise would increase reactive hyperemia as measured by digital thermal monitoring (DTM) in association to patients' cardiometabolic risk. METHODS: Thirty patients (58 ± 9 years) scheduled for noncardiac surgery were studied prospectively. Preoperatively, temperature rebound (TR) following upper arm cuff occlusion was measured before and 10 minutes after exercise. Data are presented as means ± SD. Statistical analysis utilized ANOVA and Fisher's exact test, with P values <0.05 regarded as significant. RESULTS: Following exercise, TR-derived parameters increased significantly (absolute: 0.53 ± 0.95 versus 0.04 ± 0.42°C, P=0.04, and % change: 1.78 ± 3.29 versus 0.14 ± 1.27 %, P=0.03). All patients with preoperative cardiac risk factors had a change in TR (after/before exercise, ΔTR) with values falling in the lower two tertiles of the study population (ΔTR <1.1%). CONCLUSION: Exercise increased the reactive hyperemic response to ischemia. This dynamic response was blunted in patients with cardiac risk factors. The usability of this short-term effect for the preoperative assessment of endothelial function warrants further study.
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Schier et al. (2013) conducted an observational in Scheduled for noncardiac surgery (n=30). Short-term exercise vs. Rest (before exercise) was evaluated on Absolute temperature rebound (TR) following upper arm cuff occlusion (p=0.04). Short-term exercise significantly increased absolute temperature rebound compared to rest (0.53 vs 0.04°C, P=0.04), but this dynamic response was blunted in patients with cardiac risk factors.
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