Key result
Advanced age is associated with an attenuated cardiovascular response to a head-up tilt test in both sexes, including a significantly greater fall in systolic blood pressure in older versus younger subjects (p≤0.05).
Why the study?
This study aimed to assess the age-related changes in the cardiovascular response to tilt test in healthy individuals of both sexes.
Does age affect the cardiovascular response to a head-up tilt test in healthy individuals?
Cross-Sectional (n=90)
No
Does age affect the cardiovascular response to a head-up tilt test in healthy individuals?
p-value: p=≤0.05
The aging process is associated with an attenuated cardiovascular autonomic response to orthostatic stress during a tilt test in both healthy males and females.
Lesser tilt-induced BP changes in older males; extends age-related autonomic insights but leaves open clinical relevance.
This study aimed to assess the age-related changes in the cardiovascular response to tilt test in 90 healthy individuals of both sexes (age range: 18-60 years). Tilting was done at 600 for 10 min using a motorized tilt table. The blood pressure was recorded by a sphygmomanometer. The heart rate and peripheral capillary oxygen saturation were measured by a pulse oximeter. In males, significantly lesser changes in the systolic, diastolic and mean arterial pressure were observed in the old age (47-60 years) than the young (18-32 years) and middle age (33-46 years) groups. Significantly lesser responses in the heart rate and systolic blood pressure change were observed in the old age females compared to young age after tilting. The rise of diastolic blood pressure after tilting was lesser in the old age female compared to both young and middle-age females. In conclusion, the aging process is associated with attenuated cardiovascular response to tilt test in both males and females.
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Rimi et al. (2020) conducted a cross-sectional in Healthy volunteers (n=90). Advanced age vs. Younger age (18-32 years) was evaluated on Maximum change in heart rate and blood pressure after tilting (p=≤0.05). Advanced age is associated with an attenuated cardiovascular response to a head-up tilt test in both sexes, including a significantly greater fall in systolic blood pressure in older versus younger subjects (p≤0.05).
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