Why the study?
Does a rapid 90-minute rule-out method using cardiac biomarkers improve diagnostic efficiency and reduce CCU admissions compared to chest pain observation units in patients at risk of myocardial infarction?
Does a rapid 90-minute rule-out method using cardiac biomarkers improve diagnostic efficiency and reduce CCU admissions compared to chest pain observation units in patients at risk of myocardial infarction?
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A rapid 90-minute rule-out method using multiple cardiac biomarkers may offer a highly sensitive alternative to resource-intensive chest pain observation units for assessing suspected myocardial infarction.
It has been suggested that chest pain observation units are a cost effective solution to the risks inherent in assessing patients at risk of myocardial infarction and its sequelae within emergency departments in the UK. Their function requires that patients are monitored closely for several hours, and they consume significant resources. An alternative is the use of a rapid 90 minute rule-out method, incorporating myoglobin along with creatine kinase-MB (CK-MB) and troponin I.2,3 This has a sensitivity and negative predictive value of 100% for myocardial infarction, reduces coronary care unit (CCU) admissions by 40%, and does not require a dedicated observation unit. …
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F G Dunn (2006) studied this question.
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