The association between pseudoexfoliation and metabolic syndrome, a case control study

Introduction: Pseudoexfoliation Syndrome (PXS) is a systemic disease which is characterized by creation of fibro-granular materials in the anterior segment of the eye. PXS is also known as a risk factor for vascular blockages in the arteries and veins of the retina. Given the existing information about PXS, the present study was done to perform a comparative study on the prevalence of metabolic syndrome in patients suffering PXS with control group Methods: This case-control study was performed on 50 patients with PXS and 35 healthy people who are with patients referred to other clinics that were matched by sex and age with case groups. PXS was diagnosed with slit lamp by an ophthalmologist. Subjects checked for clinical examinations including blood pressure, height, weight, waist circumference by standard methods. A 12 hours fasted blood sample taken for determining Triglyceride, Cholesterol, HDL, LDL, and Fasting Blood Sugar. Metabolic syndrome defined according to the (NCEP ATP III) criteria. Data were entered into SPSS (Version22) and analyzed using chi-square test. Significance level of P was considered 0.05