Obstacle for Promising Cancer Therapy

Cancer cells are wily. Drug therapies may temporarily halt tumor growth, but all too often the agents lose their effectiveness as the cells' genetic versatility allows them to become resistant. Researchers hoped that so-called antiangiogenesis therapies, which are aimed at preventing the growth of the new blood vessels needed to nourish tumors rather than at the tumors themselves, might circumvent this problem. But recent work suggests that tumors may be able to get around angiogenesis inhibitors, too.