Why the study?
Postural orthostatic tachycardia syndrome can remain undiagnosed for years and is often mistaken for an anxiety disorder due to its hyperadrenergic manifestations.
POTS is often misdiagnosed as an anxiety disorder due to hyperadrenergic manifestations, highlighting the need for accurate diagnosis and appropriate management.
Raises awareness of POTS misdiagnosis as anxiety in practice; hypothesis-generating and requires prospective studies before guiding care.
Dizziness can be protean with multiple phenotypes. One common phenotype in the young population is postural orthostatic tachycardia syndrome (POTS). POTS has a unique cardiovascular signature with a fascinating range of etiologies and pharmacodynamic substrates. This condition can pass undiagnosed for many years and is often mistaken as an anxiety disorder due to some of its hyperadrenergic manifestations. We present one such case and then flesh out the treatment strategies, both conservative and pharmacologic. We finally describe the various underlying pathophysiologic mechanisms of POTS and its sub-types and outline the various aberrant cardiovascular reflexes. We also describe the power spectra of the heart rate variability frequency bands and their underlying physiologic basis.
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Hassan Kesserwani (2020) studied this question.
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