A series of Schiff bases (4a-j) were prepared by reacting 4‐amino‐5‐(1‐phenylethyl)‐2,4‐dihydro‐3 H ‐1,2,4‐triazole‐3‐thione and substituted aromatic aldehydes. The chemical structures were confirmed by means of UV, 1 H NMR, IR, MS(API‐ES) spectral data and elemental analysis. All the synthesized compounds were screened for their antimicrobial activity. Among the tested compounds, Schiff bases with 4‐OH and 4‐NO 2 substituent exhibited remarkable antimicrobial activity against all the tested microorganism.
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Çalişir et al. (2010) studied this question.
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