Why the study?
Does pregnancy increase the risk of subsequent events in patients with prior spontaneous coronary artery dissection?
Does pregnancy increase the risk of subsequent events in patients with prior spontaneous coronary artery dissection?
This case series aims to evaluate the risk of recurrent cardiovascular events in women who become pregnant following a spontaneous coronary artery dissection.
Pregnancy after SCAD warrants individualized counseling and surveillance; this case series leaves open the magnitude of recurrent event risk.
Letters21 April 2015Pregnancy After Spontaneous Coronary Artery Dissection: A Case SeriesMarysia S. Tweet, MD, Sharonne N. Hayes, MD, Rajiv Gulati, MD, PhD, Carl H. Rose, MD, and Patricia J.M. Best, MDMarysia S. Tweet, MDFrom Mayo Clinic College of Medicine, Rochester, Minnesota., Sharonne N. Hayes, MDFrom Mayo Clinic College of Medicine, Rochester, Minnesota., Rajiv Gulati, MD, PhDFrom Mayo Clinic College of Medicine, Rochester, Minnesota., Carl H. Rose, MDFrom Mayo Clinic College of Medicine, Rochester, Minnesota., and Patricia J.M. Best, MDFrom Mayo Clinic College of Medicine, Rochester, Minnesota.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/L14-0446 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Background: Spontaneous coronary artery dissection (SCAD) is an increasingly recognized and potentially fatal cause of myocardial infarction (MI) that predominantly affects young women (1, 2). Pregnancy is considered a contributory factor in approximately 12% to 30% of events (1, 3, 4) and recurrence is now recognized, with 10-year Kaplan–Meier estimated rates as high as 29% (1). Current recommendations to avoid pregnancy after SCAD are based on the presumed increased risk for recurrence with pregnancy, although, to our knowledge, assessment of pregnancy after SCAD has not been described.Objective: To determine the risk for subsequent events in patients who became pregnant ...References1. Tweet MS, Hayes SN, Pitta SR, Simari RD, Lerman A, Lennon RJ, et al. Clinical features, management, and prognosis of spontaneous coronary artery dissection. Circulation. 2012;126:579-88. [PMID: 22800851] doi:10.1161/CIRCULATIONAHA.112.105718 CrossrefMedlineGoogle Scholar2. Tweet MS, Eleid MF, Best PJ, Lennon RJ, Lerman A, Rihal CS, et al. Spontaneous coronary artery dissection: revascularization versus conservative therapy. Circ Cardiovasc Interv. 2014;7:777-86. [PMID: 25406203] doi:10.1161/CIRCINTERVENTIONS.114.001659 CrossrefMedlineGoogle Scholar3. Thompson EA, Ferraris S, Gress T, Ferraris V. Gender differences and predictors of mortality in spontaneous coronary artery dissection: a review of reported cases. J Invasive Cardiol. 2005;17:59-61. [PMID: 15640544] MedlineGoogle Scholar4. Mortensen KH, Thuesen L, Kristensen IB, Christiansen EH. Spontaneous coronary artery dissection: a Western Denmark Heart Registry study. Catheter Cardiovasc Interv. 2009;74:710-7. [PMID: 19496145] doi:10.1002/ccd.22115 CrossrefMedlineGoogle Scholar5. Eleid MF, Guddeti RR, Tweet MS, Lerman A, Singh M, Best PJ, et al. Coronary artery tortuosity in spontaneous coronary artery dissection: angiographic characteristics and clinical implications. Circ Cardiovasc Interv. 2014;7:656-62. [PMID: 25138034] doi:10.1161/CIRCINTERVENTIONS.114.001676 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Mayo Clinic College of Medicine, Rochester, Minnesota.Acknowledgment: The authors thank the patients participating in the Mayo Clinic SCAD Registry and acknowledge Jill Boyum; Michelle Schoeppner; Diane Vrieze; and Sue Ward, RN, for their registry work.Financial Support: This study was funded in part by the Mayo Clinic Division of Cardiovascular Diseases, Chicago Mercantile Exchange Foundation, and SCAD Research, Inc.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L14-0446. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByRecurrent spontaneous coronary artery dissectionPregnancy-Associated Chest Pain: A Case of Spontaneous Coronary Artery DissectionAcute Coronary Syndromes in PregnancySpontaneous Coronary Artery DissectionSpontaneous Coronary-Artery DissectionPregnancy After Spontaneous Coronary Artery Dissection (SCAD): a 2020 UpdateCoronary Disease in Pregnancy: Myocardial Infarction and Spontaneous Coronary Artery DissectionAssociation of Pregnancy With Recurrence of Spontaneous Coronary Artery Dissection Among Women With Prior Coronary Artery DissectionSpontaneous Coronary Artery DissectionCardiovascular Considerations in Caring for Pregnant Patients: A Scientific Statement From the American Heart AssociationMaternal and neonatal outcomes in women with history of coronary artery diseaseSpontaneous Coronary Artery Dissection: Mechanisms, Diagnosis and ManagementAcute Myocardial Infarction and PregnancySpontaneous coronary artery dissection: etiology and recurrenceSpontaneous coronary artery dissections and fibromuscular dysplasia: Current insights on pathophysiology, sex and genderKommentar zu den Leitlinien (2018) der ESC zum Management von kardiovaskulären Erkrankungen in der SchwangerschaftPregnancy in women with pre-existent ischaemic heart disease: a systematic review with individualised patient dataSpontaneous coronary artery dissection: a review of complications and management strategiesUpdate 2018 der ESC-Leitlinie zu kardiovaskulären Erkrankungen in der SchwangerschaftSpontaneous coronary artery dissection: contemporary aspects of diagnosis and patient managementEuropean Society of Cardiology, acute cardiovascular care association, SCAD study group: a position paper on spontaneous coronary artery dissection2018 ESC Guidelines for the management of cardiovascular diseases during pregnancyPregnancy-Associated Myocardial InfarctionSpontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart AssociationSpontaneous coronary artery dissection in women: What is known and what is yet to be understoodThe spectrum of spontaneous coronary artery dissection: illustrated review of the literatureSpontaneous Coronary Artery Dissection and PregnancySpontaneous coronary artery dissectionPregnancy and the Risk of Spontaneous Coronary Artery DissectionSpontaneous Coronary Artery Dissection in PregnancyThorakale Schmerzen in der 32. SchwangerschaftswocheSpontaneous Coronary Artery DissectionFocused Cardiovascular Care for WomenWhat Clinicians Should Know Αbout Spontaneous Coronary Artery Dissection 21 April 2015Volume 162, Issue 8Page: 598-600KeywordsCesarean sectionCoronary arteriesDisclosureMultiple sclerosisPlacentaPosttraumatic stress disorderPregnancyRisk managementSystemic mastocytosisTransient ischemic attacks ePublished: 21 April 2015 Issue Published: 21 April 2015 CopyrightCopyright © 2015 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
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