Ehlers-Danlos Syndrome Occurring Together with the Marfan Syndrome

THOUGH the classic features of the Marfan syndrome (arachnodactyly, ectopia lentis and aortic lesions) and those of the Ehlers-Danlos syndrome (joint hypermobility and hyperelasticity and fragility of the skin) are well recognized1 many are not aware of the clinical overlap existing in these and other heritable disorders of connective tissue.The present report describes a patient with valvular heart disease who had the classic features of both of the genetically determined disorders mentioned above — an observation not known to have been reported previously. Other facets of this report stress the possible relation between these two diseases, with a brief . . .