Spread of genetically similar noroviruses in Bangkok, Thailand, through symptomatic and asymptomatic individuals

Figures

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  Figure 1. Phylogenetic tree analyses of GI.3 strains. (A) Phylogenetic tree based on nucleotide sequences. (B) Phylogenetic tree based on amino acid sequences. The reference strain U04469 and the strain identified in a community resident with an episode of diarrhea are indicated by a diamond and a circle, respectively. Clusters are indicated by square brackets with Roman numerals. (C) Alignment of the amino acid sequence of the amino-terminal region of the VP1 protein. Amino acid residues distinct from that of the reference strain are shown in white letters on a black background. Strains identified in our studies and in community residents with an episode of diarrhea are shown in bold and underline, respectively. The year and country in which the virus was detected are shown. NA, not applicable. Amino acid residues conserved in the listed strains are indicated by asterisks.

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  Figure 2. Phylogenetic tree analyses of GII.2 strains identified in Thailand. (A) Phylogenetic tree based on nucleotide sequences. (B) Phylogenetic tree based on amino acid sequences. The reference strain X81879 and the strains detected in community residents with an episode of diarrhea are indicated by a diamond and circles, respectively. Clusters are indicated by square brackets with Roman numerals. (C) Alignment of amino acid sequence of the amino-terminal region of the VP1 protein. Amino acid residues distinct from that of the reference strain are shown in white letters on a black background. Strains identified in our studies and in community residents with an episode of diarrhea are shown in bold and underline, respectively. Amino acid residues conserved in the listed strains are indicated by asterisks.

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  Figure 3. Phylogenetic tree analyses of GII.8 strains identified in Thailand. (A) Phylogenetic tree based on nucleotide sequences. (B) Phylogenetic tree based on amino acid sequences. The reference strain AF195848 and the strain identified in community residents with an episode of diarrhea are indicated by a diamond and a circle, respectively. Clusters are indicated by square brackets with Roman numerals. (C) Alignment of the amino acid sequence of the amino-terminal region of the VP1 protein. Amino acid residues distinct from that of the reference strain are shown in white letters on a black background. Strains identified in our studies and in community residents with an episode of diarrhea are shown in bold and underline, respectively. Amino acid residues conserved in the listed strains are indicated by asterisks.

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  Figure 4. Phylogenetic tree analyses of GII.4 strains. (A) Phylogenetic tree based on nucleotide sequences. (B) Phylogenetic tree based on amino acid sequences. The reference strain X76716 and a strain identified in a community resident with an episode of diarrhea are indicated by a diamond and a circle, respectively. The strains with the A8V substitution identified by our group and another group are indicated by squares and triangles, respectively.

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  Figure 5. Alignment of VP1 protein amino acid sequences of previously identified GII.4 strains with amino acid substitutions. Amino acid residues distinct from those of the reference strain X81879 are shown in white letters on a black background. The year and country of the sample in which the virus was detected and the variant name are listed next to the sequence.