A relatively large amount of enterotoxin B (125 mug/ml) was produced in a synthetic medium composed of amino acids, inorganic salts, and vitamins. This medium was prepared on the basis of the utilization of the various amino acids by Staphylococcus aureus strain S-6 throughout the growth cycle. Arginine appeared to be essential for enterotoxin production. The pattern of enterotoxin production in the synthetic media appeared to differ from that in complex media.
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Wu et al. (1971) studied this question.
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