Why the study?
How do hypoxic hypoxia and carbon monoxide hypoxia affect closing pressure, systemic arterial resistance, and compliance in the canine systemic arterial circulation?
Population
Anesthetized dogs with cardiac bypass and constant ventilation
Comparison
Hypoxic hypoxia and carbon monoxide hypoxia vs Comparison between hypoxic hypoxia and carbon…
Design
Preclinical
Authors
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Distinct canine arterial responses to hypoxia types caution against uniform assumptions; leaves open human mechanistic and clinical relevance.
How do hypoxic hypoxia and carbon monoxide hypoxia affect closing pressure, systemic arterial resistance, and compliance in the canine systemic arterial circulation?
Hypoxic hypoxia and carbon monoxide hypoxia exert qualitatively different effects on systemic arterial closing pressure and vasomotor tone in a canine model.
Sylvester et al. (1981) studied this question.
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