Why the study?
How do various types of bariatric surgery influence the levels of adipokines and incretins in patients with obesity?
How do various types of bariatric surgery influence the levels of adipokines and incretins in patients with obesity?
This review highlights the mechanisms by which bariatric surgery influences adipokines and incretins to regulate metabolism in obesity.
May guide targeted metabolic therapies post-bariatric surgery; leaves open prospective validation before clinical adoption.
The growth of obesity and type 2 diabetes incidence has made bariatric surgery a widespread method of treatment. The effectiveness of bariatricoperations in the treatment of obesity and related metabolic diseases is thoroughly highlighted in medical literature. However, the resultsof surgery do not always correlate with type of operation. As before, the mechanisms have not been fully studied of how the bariatric surgeryinfluence on insulinresistance, entero-insulin axes, adipokines. Understanding such mechanisms will allow us to determine more precisely theindications relating to surgical treatment, and enhance the effectiveness of surgery in specific patient. The review is focusing on the influence ofvarious types of bariatric surgery on the level of adipokines and incretines that participate in regulation of appetite and of fat and carbohydratemetabolism. The article elaborates modern concepts related to the impact of bariatric operations on metabolic disorders in obesity.
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Babenko et al. (2014) studied this question.
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