Why the study?
Are 25-hydroxyvitamin D levels associated with the presence of cardiovascular autonomic neuropathy in patients with type 1 diabetes mellitus?
Are 25-hydroxyvitamin D levels associated with the presence of cardiovascular autonomic neuropathy in patients with type 1 diabetes mellitus?
Low vitamin D may link to CAN in T1DM; leaves open whether supplementation modifies risk.
Low levels of vitamin D have been suggested to have a negative effect on the pancreatic β cell function, being associated with insulin resistance and an increase in inflammatory markers in diabetic patients. However, the relationship between vitamin D levels and diabetes microvascular complications has not been well established yet. This study aimed to evaluate the association between the levels of 25-hydroxyvitamin D [25(OH)D] and the presence of cardiovascular autonomic neuropathy (CAN) in patients with type 1 Diabetes Mellitus (T1D).
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Silva et al. (2015) studied this question.
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