In Helix, activation of an identified serotonin-containing neurone produces a slow, markedly voltage-sensitive, depolarizing synaptic potential in another identified neurone, the A neurone. Accommodation of impulse activity in the A neurone observed with repetitive applied constant-amplitude pulses is markedly reduced by activating the serotonin neurone. Activation of the serotonin neurone also prolongs the duration of the A neurone action potential.
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Choi et al. (2008) studied this question.
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