Collateral circulation induced by chronic subclavian vein thrombosis can cause false-positive bone metastasis findings on 18F-choline PET/CT.
Apparent bone uptake on 18F-choline PET/CT may be artifactual with central venous thrombosis; hypothesis-generating and requires prospective validation.
We report the case of a 71-year-old man undergoing initial assessment for a high-risk group prostate adenocarcinoma. His medical history includes gastric carcinoma treated with surgery and chemotherapy. 18 F-choline PET/CT was performed for initial staging and displayed several intense foci uptake of sternum and thoracic vertebrae, suggestive of bone metastasis. Because of a chronic right jugulosubclavian confluent thrombosis related to his implantable chamber, a control was performed 3 weeks later. It showed spontaneous disappearance of those uptakes, consistent with pitfalls related to the collateral circulation induced by the chronic right subclavian vein thrombosis, despite the chronic anticoagulation.
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Pretet et al. (2023) studied this question.
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