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January 2, 2014Vascularized Composite AllotransplantationOpen Access

Inhibition of JAK/STAT Signaling Synergizes with CTLA4-Ig to Promote Transplant Survival

Madeline L. Fryer Saami Khalifian Byoungchol Oh Devin Miller Joshua D. Budihardjo W. P. Andrew Lee Gerald Brandacher Giorgio Raimondi

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Abstract

Transplant tolerance induction through conventional costimulation blockade (CoB) remains an elusive goal. Recent evidence suggests that inflammatory cytokines (IC) contribute to the activation of a...

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Fryer et al. (2014) studied this question.

synapsesocial.com/papers/6a758e4972c9f0ed5b5ffe8f https://doi.org/10.4161/23723505.2014.970877

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