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A considerable antitumor activity of Rabdosia diterpenoids, oridonin (1), enmein (2), enmein-3-acetate (3), nodosin (4), and shikoccin (5), was recognized against P 388 lymphocytic leukemia inoculated into mice. Teucrium diterpenoids, teucvin (6) and teucvidin (7), did not show any activity. A brief discussion on the activity is also described.
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Nagao et al. (1982) studied this question.
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