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Standard and novel therapeutic strategies for overt disseminated intravascular coagulation are summarized based on recent pathogenesis advances, with no quantitative results reported in the abstract.
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Disseminated intravascular coagulation (DIC) is characterized by an acute generalized, widespread activation of coagulation, which results in thrombotic complications, due to the intravascular formation of fibrin, as well as diffuse hemorrhages, due to the consumption of platelets and coagulation factors. In this review, we briefly report the present knowledge about the treatment of DIC. We focus on the current standard treatment of overt DIC in clinical practice. Moreover, particular attention is made to novel therapeutic strategies, who reflect the important progresses in the understanding of the pathogenesis of this syndrome in the last few years.
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Franchini et al. (2004) conducted a review in Disseminated intravascular coagulation (DIC). Standard and novel therapeutic strategies for DIC was evaluated. Standard and novel therapeutic strategies for overt disseminated intravascular coagulation are summarized based on recent pathogenesis advances, with no quantitative results reported in the abstract.
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