Key result
In a patient with probable vasoplegic syndrome during spine surgery, nor-epinephrine infusion successfully increased systemic vascular resistance and restored normal blood pressure.
Case Report (n=1)
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Norepinephrine infusion successfully managed severe refractory hypotension (vasoplegic syndrome) in a patient undergoing spine surgery in the prone position.
Perioperative hypotension is a well-recognized and relatively common problem during surgery. Vasoplegic syndrome is one such condition which is characterized by severe persistent hypotension with normal to high cardiac output and low systemic resistance. It is commonly seen in patients undergoing cardiac surgery on cardiopulmonary bypass. However, this syndrome has also been reported in off pump surgeries. Management of intraoperative hypotension may be challenging for an anaesthesiologist, if it does not respond or poorly respond to conventional therapy. We report the management of a hypertensive patient posted for spine surgery in prone position, who developed severe hypotension under anaesthesia refractory to treatment.
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Hazarika et al. (2015) conducted a case report in Vasoplegic syndrome / refractory intraoperative hypotension (n=1). Nor-epinephrine infusion was evaluated on Blood pressure recovery. In a patient with probable vasoplegic syndrome during spine surgery, nor-epinephrine infusion successfully increased systemic vascular resistance and restored normal blood pressure.
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