Application of Autologous Platelet Rich Plasma to Graft Donor Sites to Reduce Pain and Augment Healing: A Randomized Controlled Trial

This is the authors' abstract. We don't add key points for this paper.

Platelet Rich Plasma has been vastly utilized in the medical field due to its property to heal the wounds and the multitude of growth factors it contains. Traditionally, donor sites are left to heal with a primary dressing which would otherwise be opened as the wound heals. Various methods of donor site management have been described such as collagen dressings, hydrocolloid, alginate, hydro fiber, silicone dressing, or paraffin gauze. However, it is often encountered that there is a delay in the healing process and accompanied by pain at donor site. Furthermore, in a relatively small population of patients who have a tendency to hypertrophic scar formation, this becomes a challenge for the plastic surgeon. It not only leads to unsightly scars but also additional problems of dryness and itching. Owing to the healing properties of PRP, we designed this study to utilize it for donor site dressings following split thickness skin grafts. This study primarily throws light on the usage of Autologous PRP over Split thickness Skin Graft donor sites to augment healing, and reduce pain.