Why the study?
Does Sairei-To improve pregnancy success rates in patients with recurrent abortion and positive antiphospholipid antibodies?
Does Sairei-To improve pregnancy success rates in patients with recurrent abortion and positive antiphospholipid antibodies?
Sairei-To may be an effective treatment for improving pregnancy outcomes in patients with recurrent abortion and positive antiphospholipid antibodies.
Hypothesis-generating for Sairei-To in recurrent abortion with antiphospholipid antibodies; prospective trials needed before clinical adoption.
Twelve patients with recurrent abortion who had shown positive antiphospholipid antibodies were treated through the administration of a Japanese modified traditional Chinese herbal medicine Sairei-To (Chan ling-Tang) The patients had experienced a total of 27 spontaneous abortions in their previous pregnancies and had no other pregnancy history except for one patient. The patients were treated with 9.0 g of Sairei-To per day before their next pregnancy. The positive value of antiphospholipid antibodies returned to negative in 9 patients out of 12 patients through the treatment. Out of 12 patients, in 10 patients, their new pregnancy continued uneventfully and delivered an offspring (Success rate: 83.3%). Thus, the current treatment was considered to be an effective therapy for patients with recurrent abortion who were found to be positive for antiphospholipid antibodies.
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Takakuwa et al. (1996) studied this question.
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